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Article

C/EBPϵ interacts with retinoblastoma and E2F1 during granulopoiesis

2 Sept 2003

Abstract excerpt

CCAAT enhancer binding protein epsilon (C/EBPepsilon) is a myeloid specific transcription factor that is essential for terminal granulocytic differentiation. Retinoblastoma (Rb) and E2F1 are critical cell cycle regulators that also have been implicated in several differentiation systems. Here, we demonstrate that C/EBPepsilon interacts with Rb and E2F1 during granulocytic differentiation in NB4 and U937 human...

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PMID: 12947005
DOI: 10.1182/blood-2003-01-0159

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