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Article

Repression of transcriptional activity of C/EBPalpha by E2F-dimerization partner complexes.

Molecular and cellular biology - 1 May 2010

Zaragoza Katrin, Bégay Valérie, Schuetz Anja, Heinemann Udo, Leutz Achim

Abstract excerpt

The transcription factor CCAAT/enhancer-binding protein alpha (C/EBPalpha) coordinates proliferation arrest and the differentiation of myeloid progenitors, adipocytes, hepatocytes, keratinocytes, and cells of the lung and placenta. C/EBPalpha transactivates lineage-specific differentiation genes and inhibits proliferation by repressing E2F-regulated genes. The myeloproliferative C/EBPalpha BRM2 mutant serves as a...

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Source

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Identifiers

PMID: 20176812
DOI: 10.1128/MCB.01619-09
PMCID: PMC2863587

Genes

EBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Repression of transcriptional activity of C/EBPalpha by E2F-dimerization partner complexes.PMID 20176812Read ↗

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