Article
Suppression of malignant phenotype of a transformed mouse mammary epithelial cell line (11A1) by tumor suppressor gene RB.
Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih - 1 Jun 1997
Wang D, Li S, Au W, Cui H, Yang X
Abstract excerpt
A malignant transformed mammary epithelial cell line (11A1) was transfected with liposome encapsulated eukaryotic expression plasmid pCMV-neo-RB, yielding 4 constant clones which have obvious phenotypic reversion changes, and named 11A1-R1-R4 respectively. Further experiments showed that the 11A1-R1 behaved like normal epithelial cells in both morphological and biological characteristics, with decreased...
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