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Article

The phenotypic reversion of cancer: Experimental evidences on cancer reversibility through epigenetic mechanisms (Review).

Oncology reports - 1 Mar 2024

Pensotti Andrea, Bizzarri Mariano, Bertolaso Marta

Abstract excerpt

Different experimental models reveal that malignant cancer cells can be induced to change their phenotype into a benign one. This phenotypic transformation, confirmed both in vitro and in vivo, currently is known as 'tumor reversion'. This evidence raises a radical question among current cancer models: Is cancer reversible? How do genetic and epigenetic alterations hierarchically relate? Understanding the...

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Identifiers

PMID: 38275101
DOI: 10.3892/or.2024.8707
PMCID: PMC10835663

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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