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Article

The role of Rac1 in maintaining malignant phenotype of mouse skin tumor cells.

Cancer letters - 18 Jan 2006

Kwei Kevin A, Finch Joanne S, Ranger-Moore James, Bowden G Tim

Abstract excerpt

We have previously developed an in vitro tumor progression model with mouse skin keratinocytes to study the molecular targets that mediate the tumor cell's progression from a benign to a malignant phenotype. The malignantly transformed cells were found to have elevated MAP kinase signaling and increases in AP-1, NFkappaB and cAMP response element (CRE) transcription factors activities compared to their benign...

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Source

Identifiers

PMID: 15893875
DOI: 10.1016/j.canlet.2005.02.031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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