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Article

All trans-retinoic acid (ATRA) induces re-differentiation of early transformed breast epithelial cells

21 Mar 2014

Abstract excerpt

Retinoids have been used as potential chemotherapeutic or chemopreventive agents because of their differentiative, anti-proliferative, pro-apoptotic and antioxidant properties. We investigated the effect of all trans-retinoic acid (ATRA) at different stages of the neoplastic transformation using an in vitro model of breast cancer progression. This model was previously developed by treating the MCF-10F human...

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PMID: 24676586
DOI: 10.3892/ijo.2014.2354

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