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Article

Phenotypic and genotypic analysis of rat liver epithelial cells infected with retroviral shuttle vectors.

Cancer letters - 1 Oct 1996

Dees C, Travis C

Abstract excerpt

Rat liver epithelial cells (RLE) are suspected to be pluripotent hepatic stem cells that give rise to a diverse variety of liver tumors. The molecular events responsible for transformation of these cells and the diversity of the tumor phenotypes remains to be fully elucidated. We examined the genotype and phenotype of RLE cells infected with retroviral shuttle vectors carrying a neomycin resistance (neor) Ha-ras...

Topics

Animals
Blotting, Northern
Cell Division
Cell Transformation, Neoplastic
Colony-Forming Units Assay
DNA Mutational Analysis
Drug Resistance
Epithelium
Genetic Vectors
Genotype
Liver

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Nude

Neomycin

Phenotype

Rats

Retroviridae

Tumor Suppressor Protein p53

Source

Identifiers

PMID: 8913262
DOI: 10.1016/0304-3835(96)04338-8

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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