Article
Membrane proximal ERK signaling is required for M-calpain activation downstream of epidermal growth factor receptor signaling.
The Journal of biological chemistry - 29 Jun 2001
Glading A, Uberall F, Keyse S M, Lauffenburger D A, Wells A
Abstract excerpt
Localization of signaling is critical in directing cellular outcomes, especially in pleiotropic signaling pathways. The extracellular signal-regulated kinase (ERK)/microtubule-associated protein kinase, which promotes cell migration, proliferation, and differentiation is found in the nucleus and...
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