Article
Basal extracellular signal-regulated kinase activity modulates cell-cell and cell-matrix interactions.
Molecular and cellular biology - 1 Jun 1998
Lu Q, Paredes M, Zhang J, Kosik K S
Abstract excerpt
Suppression of the basal extracellular signal-regulated kinase (ERK) activity in PC12 cells markedly altered their phenotype. Wild-type cells grew in a dissociated pattern adherent to the substrate. The stable expression of an ERK inhibitory mutant resulted in the formation of calcium-dependent a...
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