Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Growth-inhibitory effect of adenovirus-mediated p53 gene transfer on medulloblastoma cell line, Daoy, harboring mutant p53.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery - 1 Feb 2001

Lee S H, Kang H S, Rhee C H, Kim M S, Kwon H C, Park M J, Park I C, Lee C T, Kim C M, Hong S I

Abstract excerpt

To improve the survival rate, gene therapy, such as the replacement of inactivated tumor suppressor genes, has become a new investigational adjuvant treatment modality for human malignancies. We investigated the effect of adenovirus(Ad)-mediated transfer of wildtype p53 tumor suppressor gene on the medulloblastoma cell line, Daoy, which harbors mutant-type p53 gene. At 50 multiplicity of infection (moi),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenoviruses, Human
Share to Cell Division

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line, Transformed

Share to Gene Transfer Techniques

Share to Genes, p53

Share to Genes, Tumor Suppressor

Share to Genetic Therapy

Share to Medulloblastoma

Source

Identifiers

PMID: 11305765
DOI: 10.1007/s003810000341

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Growth-inhibitory effect of adenovirus-mediated p53 gene transfer on medulloblastoma cell line, Daoy, harboring mutant p53.PMID 11305765Read ↗

Advances in adenovirus-mediated p53 cancer gene therapySemantic proximity Read ↗

Clinical utility of recombinant adenoviral human p53 gene therapy: current perspectivesSemantic proximity Read ↗

Adenovirus-mediated p53 gene transfer inhibits growth of human tumor cells expressing mutant p53 protein.Semantic proximity Read ↗

Suppression of tumor growth using a recombinant adenoviral vector carrying the dominant-negative mutant gene Survivin-D53A in a nude mice model.Semantic proximity Read ↗

Adenovirus-mediatedp53 gene transfer suppresses growth of human glioblastoma cellsin vitro andin vivoSemantic proximity Read ↗

Adenovirus-mediated p53 growth inhibition of ovarian cancer cells is independent of endogenous p53 status.Semantic proximity Read ↗

Enhancement of radiosensitivity of wild-type p53 human glioma cells by adenovirus-mediated delivery of the p53 gene.Semantic proximity Read ↗

Analysis of a mutant p53 protein arising in a medulloblastoma from a mouse transgenic for the JC virus early region.Semantic proximity Read ↗

Identification of a novel p53 mutation in JCV-induced mouse medulloblastoma.Semantic proximity Read ↗

Induction of efficient apoptosis and cell-cycle arrest in tumor cells by adenovirus-mediated p53 A4 mutant.Semantic proximity Read ↗

Adenovirus-mediated tumor suppressor p53 gene therapy for anaplastic thyroid carcinoma in vitro and in vivo.Semantic proximity Read ↗

Effects of adenoviral wild-type p53 gene transfer in p53-mutated lymphoma cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.