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Article

Adenovirus-mediated p53 growth inhibition of ovarian cancer cells is independent of endogenous p53 status.

Gynecologic oncology - 1 Nov 1999

Wolf J K, Mills G B, Bazzet L, Bast R C, Roth J A, Gershenson D M

Abstract excerpt

OBJECTIVE: The aim of this study was to determine the effect of transfection of adenovirus-mediated wild-type p53 into ovarian cancer cells with both wild-type and mutant endogenous p53. STUDY DESIGN: Eight human ovarian cancer cell lines were used: three with p53 mutations, one that is p53 null, and four with wild-type p53. The recombinant p53 adenovirus (Adp53) contains the cytomegalovirus promoter, wild-type...

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Share to Adenoviridae
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Share to Genes, p53

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10525383
DOI: 10.1006/gyno.1999.5565

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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