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Article

Nicotine metabolism and CYP2D6 phenotype in smokers.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2001

Caporaso N E, Lerman C, Audrain J, Boyd N R, Main D, Issaq H J, Utermahlan B, Falk R T, Shields P

Abstract excerpt

We tested the hypothesis that the polymorphic enzyme CYP2D6 is related to nicotine metabolism in 261 healthy subjects enrolling in a smoking cessation clinic. Subjects completed a questionnaire, were given dextromethorphan, and contributed a urine and blood sample. The CYP2D6 phenotype (based on a determination of dextromethorphan and metabolites in an aliquot of overnight urine) and genotype (based on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 11303596

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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