Article
Nicotine dependence pharmacogenetics: role of genetic variation in nicotine-metabolizing enzymes.
Journal of neurogenetics - 1 Jan 2009
Ray Riju, Tyndale Rachel F, Lerman Caryn
Abstract excerpt
Nicotine-dependence pharmacogenetics research is an emerging field, and a number of studies have begun to characterize the clinical relevance and predictive power of genetic variation in drug-metabolizing enzymes and drug target genes for response to medication. The present paper focuses on evidence for the role of nicotine-metabolizing enzymes in smoking behavior and response to treatment. Nicotine metabolism is...
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