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Article

Complexity and power in case-control association studies.

American journal of human genetics - 1 May 2001

Longmate J A

Abstract excerpt

A general method is described for estimation of the power and sample size of studies relating a dichotomous phenotype to multiple interacting loci and environmental covariates. Either a simple case-control design or more complex stratified sampling may be used. The method can be used to design individual studies, to evaluate the power of alternative test statistics for complex traits, and to examine general...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11294658
DOI: 10.1086/320106
PMCID: PMC1226103

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