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Article

Epistasis, complexity, and multifactor dimensionality reduction.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013

Pan Qinxin, Hu Ting, Moore Jason H

Abstract excerpt

Genome-wide association studies (GWASs) and other high-throughput initiatives have led to an information explosion in human genetics and genetic epidemiology. Conversion of this wealth of new information about genomic variation to knowledge about public health and human biology will depend critically on the complexity of the genotype to phenotype mapping relationship. We review here computational approaches to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23756906
DOI: 10.1007/978-1-62703-447-0_22

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