Article
Interleukin-10-deficient mice and inflammatory bowel disease associated cancer development.
Carcinogenesis - 1 Apr 2001
Sturlan S, Oberhuber G, Beinhauer B G, Tichy B, Kappel S, Wang J, Rogy M A
Abstract excerpt
Interleukin-10-deficient mice develop colitis and colorectal cancer similar to the inflammatory bowel disease associated cancer in humans. The aim of this study was to identify possible mutations of oncogenes and tumour suppressor genes involved in tumorigenesis in Interleukin-10 (IL-10)-deficien...
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