Article

DNA methylation within intron 2 of the <i>Stat1</i> gene is reduced in colon tissue from interleukin-10 gene-deficient mice compared with healthy control mice

2015-09-25

Abstract excerpt

<h4>Background: </h4> Epigenetic influences have been implicated in the development of autoimmunity. While such mechanisms have been linked to mouse models of intestinal inflammation, and to human inflammatory bowel disease (IBD), the involvement of epigenetic mechanisms in the pathogenesis of intestinal inflammation in the interleukin-10 gene-deficient ( Il10 –/– ) mouse model of IBD has not yet been reported....

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Literature Corpus work: 50525125-95be-5a85-936e-906e7b498d83
DOI: 10.7287/peerj.preprints.1391v1

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