Article
The molecular basis of myocardial hypertrophy and heart failure.
Trends in molecular medicine - 1 Jul 2003
Ritter Oliver, Neyses Ludwig
Abstract excerpt
Heart failure (HF) is the inability of the heart to cope with the metabolic demands of the periphery. It is the common end-stage of many frequent cardiac diseases and is characterized by relentless progression. Mechanisms of progression include renal sodium and water retention, neurohumoral activation and alterations of the protein composition (gene programme) of the heart itself. In this review, we explain the...
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