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Article

Tn7 recognizes transposition target structures associated with DNA replication using the DNA-binding protein TnsE.

Genes & development - 15 Mar 2001

Peters J E, Craig N L

Abstract excerpt

We report that the bacterial transposon Tn7 selects targets by recognizing features associated with DNA replication using the transposon-encoded DNA-binding protein TnsE. We show that Tn7 transposition directed by TnsE occurs in one orientation with respect to chromosomal DNA replication, indicating that a structure or complex involved in DNA replication is likely to be a critical determinant of TnsE insertion....

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Identifiers

PMID: 11274058
DOI: 10.1101/gad.870201
PMCID: PMC312648

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