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Article

Enhancement and rescue of target capture in Tn10 transposition by site-specific modifications in target DNA.

Molecular microbiology - 1 May 2004

Pribil Patrick A, Wardle Simon J, Haniford David B

Abstract excerpt

The bacterial transposon Tn10 inserts preferentially into specific target sequences. This insertion specificity appears to be linked to the ability of target sites to adopt symmetrically positioned DNA bends after binding the transposition machinery. Target DNA bending is thought to permit the transposase protein to make additional contacts with the target DNA, thereby stabilizing the target complex so that the...

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Identifiers

PMID: 15130133
DOI: 10.1111/j.1365-2958.2004.04046.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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