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Article

Target DNA bending is an important specificity determinant in target site selection in Tn10 transposition.

Journal of molecular biology - 4 Jul 2003

Pribil Patrick A, Haniford David B

Abstract excerpt

The bacterial transposon Tn10 inserts preferentially into specific DNA sequences. DNA footprinting and interference studies have revealed that the Tn10-encoded transposase protein contacts a large stretch of target DNA ( approximately 24 bp) and that the target DNA structure is deformed upon incorporation into the transpososome. Target DNA deformation might contribute significantly to target site selection and...

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Identifiers

PMID: 12823965
DOI: 10.1016/s0022-2836(03)00588-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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