Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gain-of-function mutations in TnsC, an ATP-dependent transposition protein that activates the bacterial transposon Tn7.

Genetics - 1 Mar 1997

Stellwagen A E, Craig N L

Abstract excerpt

The bacterial transposon Tn7 encodes five genes whose protein products are used in different combinations to direct transposition to different types of target sites. TnsABC + D directs transposition to a specific site in the Escherichia coli chromosome called attTn7, whereas TnsABC + E directs transposition to non-attTn7 sites. These transposition reactions can also recognize and avoid "immune" targets that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphate
Share to Bacterial Proteins
Share to DNA, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to DNA Transposable Elements

Share to Escherichia coli

Share to Escherichia coli Proteins

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 9055068
DOI: 10.1093/genetics/145.3.573
PMCID: PMC1207843

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gain-of-function mutations in TnsC, an ATP-dependent transposition protein that activates the bacterial transposon Tn7.PMID 9055068Read ↗

Analysis of gain-of-function mutants of an ATP-dependent regulator of Tn7 transposition.Semantic proximity Read ↗

Isolation and characterization of Tn7 transposase gain-of-function mutants: a model for transposase activation.Semantic proximity Read ↗

Alternative interactions between the Tn7 transposase and the Tn7 target DNA binding protein regulate target immunity and transposition.Semantic proximity Read ↗

The Tn7 transposase is a heteromeric complex in which DNA breakage and joining activities are distributed between different gene products.Semantic proximity Read ↗

Conformational toggling controls target site choice for the heteromeric transposase element Tn7.Semantic proximity Read ↗

A minimal system for Tn7 transposition: the transposon-encoded proteins TnsA and TnsB can execute DNA breakage and joining reactions that generate circularized Tn7 species.Semantic proximity Read ↗

Tn7 recognizes transposition target structures associated with DNA replication using the DNA-binding protein TnsE.Semantic proximity Read ↗

Bacterial transposon Tn7 utilizes two different classes of target sites.Semantic proximity Read ↗

Tn5 transposase active site mutants.Semantic proximity Read ↗

Unlocking Tn3-family transposase activity in vitro unveils an asymetric pathway for transposome assembly.Semantic proximity Read ↗

Separate structural and functional domains of Tn4430 transposase contribute to target immunity.Semantic proximity Read ↗

Functional analysis of the catalytic triad of the hAT-family transposase TcBuster.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.