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Article

The Drosophila homolog of the human AF10 is an HP1-interacting suppressor of position effect variegation.

EMBO reports - 1 Mar 2001

Linder B, Gerlach N, Jäckle H

Abstract excerpt

In chromosomal rearrangements of acute myeloid leukaemia patients the mixed lineage leukaemia (MLL) gene, a human homolog of the Drosophila gene trithorax, is frequently fused to AF10. Here we describe the identification and a functional characterization of the Drosophila homolog dAF10. We show t...

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Share to Chromobox Protein Homolog 5
Share to Chromosomal Proteins, Non-Histone
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heterochromatin

Share to Histone-Lysine N-Methyltransferase

Share to Myeloid-Lymphoid Leukemia Protein

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Identifiers

PMID: 11266362
DOI: 10.1093/embo-reports/kve039
PMCID: PMC1083836

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11266362-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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The Drosophila homolog of the human AF10 is an HP1-interacting suppressor of position effect variegation.PMID 11266362Read ↗

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