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Article

Transcriptional adaptor ADA3 of Drosophila melanogaster is required for histone modification, position effect variegation, and transcription.

Molecular and cellular biology - 1 Jan 2008

Grau Benjamin, Popescu Cristina, Torroja Laura, Ortuño-Sahagún Daniel, Boros Imre, Ferrús Alberto

Abstract excerpt

The Drosophila melanogaster gene diskette (also known as dik or dAda3) encodes a protein 29% identical to human ADA3, a subunit of GCN5-containing histone acetyltransferase (HAT) complexes. The fly dADA3 is a major contributor to oogenesis, and it is also required for somatic cell viability. dADA3 localizes to chromosomes, and it is significantly reduced in dGcn5 and dAda2a, but not in dAda2b, mutant backgrounds....

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Identifiers

PMID: 17967867
DOI: 10.1128/MCB.01307-07
PMCID: PMC2223303

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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