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Article

MLL-AF9-induced leukemogenesis requires coexpression of the wild-type Mll allele.

Cancer cell - 17 Feb 2010

Thiel Austin T, Blessington Peter, Zou Tao, Feather Danielle, Wu Xinjiang, Yan Jizhou, Zhang Hui, Liu Zuguo, Ernst Patricia, Koretzky Gary A, Hua Xianxin

Abstract excerpt

Oncogenic fusion proteins are capable of initiating tumorigenesis, but the role of their wild-type counterparts in this process is poorly understood. The mixed lineage leukemia (MLL) gene undergoes chromosomal translocations, resulting in the formation of oncogenic MLL fusion proteins (MLL-FPs)....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20159607
DOI: 10.1016/j.ccr.2009.12.034
PMCID: PMC2830208

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20159607-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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