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Article

Transcriptional repression of euchromatic genes by Drosophila heterochromatin protein 1 and histone modifiers.

Proceedings of the National Academy of Sciences of the United States of America - 25 Sept 2001

Hwang K K, Eissenberg J C, Worman H J

Abstract excerpt

In Drosophila, heterochromatin protein 1 (HP1) suppresses the expression of euchromatic genes that are artificially translocated adjacent to heterochromatin by expanding heterochromatin structure into neighboring euchromatin. The purpose of this study was to determine whether HP1 functions as a transcriptional repressor in the absence of chromosome rearrangements. Here, we show that Drosophila HP1 normally...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11562500
DOI: 10.1073/pnas.211303598
PMCID: PMC58745

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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