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Article

Mannose-binding lectin (MBL) in health and disease.

Immunobiology - 1 Aug 1998

Turner M W

Abstract excerpt

Mannose-binding lectin (MBL) is the most intensively studied human collectin. It is recognized to be a versatile macro-molecule with many of the functional characteristics of IgM, IgG and Clq. In the presence of calcium the protein can bind to a wide spectrum of oligosaccharides through multiple lectin domains. Such binding to the repeating sugar arrays on microbial surfaces may result in direct uptake by one or...

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PMID: 9777416
DOI: 10.1016/S0171-2985(98)80037-5

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