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Article

TPH and suicidal behavior: a study in suicide completers.

Molecular psychiatry - 1 Jan 2001

Turecki G, Zhu Z, Tzenova J, Lesage A, Séguin M, Tousignant M, Chawky N, Vanier C, Lipp O, Alda M, Joober R, Benkelfat C, Rouleau G A

Abstract excerpt

An association between the gene that codes for tryptophan hydroxylase (TPH)-the rate-limiting enzyme in the synthesis of serotonin-and suicidal behavior has been investigated with some detail in samples of living subjects who attempted suicide. In this study, we investigated TPH and suicide completion, the most severe form of suicidal behavior. A relatively large sample of suicide completers (n = 101) was...

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Source

Identifiers

PMID: 11244493
DOI: 10.1038/sj.mp.4000816

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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TPH and suicidal behavior: a study in suicide completers.PMID 11244493Read ↗

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