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Article

Automethylation of G9a and its implication in wider substrate specificity and HP1 binding.

Nucleic acids research - 1 Jan 2007

Chin Hang Gyeong, Estève Pierre-Olivier, Pradhan Mihika, Benner Jack, Patnaik Debasis, Carey Michael F, Pradhan Sriharsa

Abstract excerpt

Methylation of lysine residues on histones participates in transcriptional gene regulation. Lysine 9 methylation of histone H3 is a transcriptional repression signal, mediated by a family of SET domain containing AdoMet-dependent enzymes. G9a methyltransferase is a euchromatic histone H3 lysine 9 methyltransferase. Here, G9a is shown to methylate other cellular proteins, apart from histone H3, including...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 17962312
DOI: 10.1093/nar/gkm726
PMCID: PMC2175347

Genes

SET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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