Article
Expression of activated Ras during Dictyostelium development alters cell localization and changes cell fate.
Development (Cambridge, England) - 1 Mar 2001
Jaffer Z M, Khosla M, Spiegelman G B, Weeks G
Abstract excerpt
There is now a body of evidence to indicate that Ras proteins play important roles in development. Dictyostelium expresses several ras genes and each appears to perform a distinct function. Previous data had indicated that the overexpression of an activated form of the major developmentally regulated gene, rasD, caused a major aberration in morphogenesis and cell type determination. We now show that the...
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