Article
Rap1 overexpression reveals that activated RasD induces separable defects during Dictyostelium development.
Developmental biology - 15 Oct 1997
Louis S A, Weeks G, Spiegelman G B
Abstract excerpt
One of the Dictyostelium ras genes, rasD, is expressed preferentially in prestalk cells at the slug stage of development and overexpression of this gene containing a G12T activating mutation causes the formation of aberrant multitipped aggregates that are blocked from further development (Reymond et al., 1986, Nature, 323, 340-343). The ability of the Dictyostelium rap1 gene to suppress this abnormal...
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