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Article

Synuclein‐1 is selectively up‐regulated in response to nerve growth factor treatment in PC12 cells

1 Feb 2001

Abstract excerpt

Mutations in the alpha-synuclein gene have recently been identified in families with inherited Parkinson's disease and the protein product of this gene is a component of Lewy bodies, indicating that alpha-synuclein is involved in Parkinson's disease pathogenesis. A role for normal alpha-synuclein in synaptic function, apoptosis or plasticity responses has been suggested. We show here that in rat pheochromocytoma...

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PMID: 11181836
DOI: 10.1046/j.1471-4159.2001.00114.x

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