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Article

?-synuclein is developmentally expressed in cultured rat brain oligodendrocytes

1 Jan 2000

Abstract excerpt

Although a neuronal protein, alpha-synuclein is a major component of glial cytoplasmic inclusions (GCIs) in oligodendrocytes of multiple system atrophy (MSA) brains. Because alpha-synuclein has not been identified in oligodendrocytes of normal brains, we examined cultured rat brain oligodendrocytes during in vitro development and showed that alpha-synuclein mRNA and protein are present in cultured...

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PMID: 11002283
DOI: 10.1002/1097-4547(20001001)62:1<9::aid-jnr2>3.0.co;2-u

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