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Article

Constitutive expression of interleukin-8 by Mutatect cells markedly affects their tumor biology.

Carcinogenesis - 1 Feb 2001

Haqqani A S, Sandhu J K, Birnboim H C

Abstract excerpt

Interleukin-8 (IL-8) is a chemokine for neutrophils and an angiogenic factor. Human tumors that express IL-8 may exhibit intense neutrophil infiltration and increased vascularization. Mutatect cells are a murine fibrosarcoma that can be grown as subcutaneous tumors in syngeneic C57BL/6 mice. Since neutrophils are a source of cytotoxic and genotoxic species, we constructed Mutatect cell lines that constitutively...

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Identifiers

PMID: 11181444
DOI: 10.1093/carcin/22.2.243

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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