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Article

DRB1-DQA1-DQB1 loci and multiple sclerosis predisposition in the Sardinian population.

Human molecular genetics - 1 Aug 1998

Marrosu M G, Murru M R, Costa G, Murru R, Muntoni F, Cucca F

Abstract excerpt

Multiple sclerosis (MS) is a common neurological disease caused by genetic and environmental factors. Previous genetic analyses have suggested that theMHC/HLA region on chromosome 6p21 contains an MS-predisposing component. Which of the many genes present in this region is primarily responsible f...

Topics

Adolescent
Adult
Aged
Alleles
Chromosomes, Human, Pair 6
Female
Genetic Variation
HLA-DQ Antigens
HLA-DQ alpha-Chains
HLA-DQ beta-Chains
HLA-DR Antigens
HLA-DRB1 Chains
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Italy

Male

Middle Aged

Multiple Sclerosis

Source

Identifiers

PMID: 9668164
DOI: 10.1093/hmg/7.8.1235

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9668164-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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DRB1-DQA1-DQB1 loci and multiple sclerosis predisposition in the Sardinian population.PMID 9668164Read ↗

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Association between protective and deleterious HLA alleles with multiple sclerosis in Central East Sardinia.Semantic proximity Read ↗

HLA-DRB1-DQB1 haplotypes confer susceptibility and resistance to multiple sclerosis in Sardinia.Semantic proximity Read ↗

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Interaction of loci within the HLA region influences multiple sclerosis course in the Sardinian population.Semantic proximity Read ↗

HLA-DQB1 genotype in Sardinian multiple sclerosis: evidence for a key role of DQB1 *0201 and *0302 alleles.Semantic proximity Read ↗

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