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Article

Mutation analysis of p53 in ovarian tumors by DHPLC.

Journal of biochemical and biophysical methods - 30 Jan 2001

Gross E, Kiechle M, Arnold N

Abstract excerpt

Up to now, ovarian carcinomas represent a major health problem among female cancers because they are the leading cause of death from gynecological malignancy. A high proportion of these tumors selects for mutations in the p53 gene. There is evidence that inactivation of the p53 protein could indicate poor prognosis and chemoresistance of patients. To set up a fast and sensitive test for p53 defects in tumor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11179763
DOI: 10.1016/s0165-022x(00)00153-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutation analysis of p53 in ovarian tumors by DHPLC.PMID 11179763Read ↗

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