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Article

Somatic mutation analysis of p53 and ST7 tumor suppressor genes in gastric carcinoma by DHPLC.

World journal of gastroenterology - 1 Dec 2003

Lu Chong, Xu Hui-Mian, Ren Qun, Ao Yang, Wang Zhen-Ning, Ao Xue, Jiang Li, Luo Yang, Zhang Xue

Abstract excerpt

AIM: To verify the effectiveness of denaturing high-performance liquid chromatography (DHPLC) in detecting somatic mutation of p53 gene in gastric carcinoma tissues. The superiority of this method has been proved in the detection of germline mutations, but it was not very affirmative with respect to somatic mutations in tumor specimens. ST7 gene, a candidate tumor suppressor gene identified recently at human...

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Share to Chromatography, High Pressure Liquid
Share to Chromosomes, Human, Pair 7

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Genes, p53

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Source

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Identifiers

PMID: 14669308
DOI: 10.3748/wjg.v9.i12.2662
PMCID: PMC4612027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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