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Article

Mutation of the PTEN gene in advanced cervical cancer correlated with tumor progression and poor outcome after radiotherapy.

International journal of oncology - 1 Mar 2001

Harima Y, Sawada S, Nagata K, Sougawa M, Ostapenko V, Ohnishi T

Abstract excerpt

Improvement in management of advanced cervical cancer after radiotherapy requires a better understanding of its biological behavior. PTEN/MMAC/TEP(PTEN), a candidate tumor suppressor gene located at chromosome 10q23.3, was recently identified and found to be frequently mutated in several different types of human tumors. In contrast, rare mutations of the PTEN gene have been reported in cervical cancer. The aim of...

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Share to Chromosomes, Human, Pair 10
Share to Neoplasm Staging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phosphoric Monoester Hydrolases

Share to Polymorphism, Single-Stranded Conformational

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Source

Identifiers

PMID: 11179477
DOI: 10.3892/ijo.18.3.493

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutation of the PTEN gene in advanced cervical cancer correlated with tumor progression and poor outcome after radiotherapy.PMID 11179477Read ↗

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