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Article

PTEN Gene Alterations in Lymphoid Neoplasms

1 Nov 1998

Abstract excerpt

Recently, a novel phosphatase designated PTEN/MMAC1/TEP1 and located on chromosome 10q23.3 has been implicated as a new tumor suppressor gene in human cancer. Allelic loss and mutation of this gene has been reported in epithelial derived tumors, including breast cancer and prostate cancer, and in glioblastoma multiforme. The present study was designed to evaluate the potential involvement of PTEN in the...

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Identifiers

PMID: 9787181
DOI: 10.1182/blood.v92.9.3410

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