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Article

Mutational analysis of the PTEN gene and its effects in esophageal squamous cell carcinoma.

Digestive diseases and sciences - 1 May 2011

Hou Guiqin, Lu Zhaoming, Liu Mingyue, Liu Hongmin, Xue Lexun

Abstract excerpt

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is one of the most frequently diagnosed cancers in China, but the etiology and mode of carcinogenesis of this disease remain poorly understood. The phosphatase and tensin homolog deleted from chromosome 10 (PTEN) with putative tumor suppressing is frequently mutated in many cancers. AIMS: The aim of this study was to investigate whether there exists a mutation...

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Source

Identifiers

PMID: 21116717
DOI: 10.1007/s10620-010-1474-0

Genes

PTEN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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