Article
Biofilm formation in a hydrodynamic environment by novel fimh variants and ramifications for virulence.
Infection and immunity - 1 Mar 2001
Schembri M A, Klemm P
Abstract excerpt
Type 1 fimbriae are surface-located adhesion organelles of Escherichia coli that are directly associated with virulence of the urinary tract. They mediate D-mannose-sensitive binding to different host surfaces by way of the minor fimbrial component FimH. Naturally occurring variants of FimH that bind strongly to terminally exposed monomannose residues have been associated with a pathogenicity-adaptive phenotype...
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