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Transposon Mutagenesis Identifies Uropathogenic Escherichia coli Biofilm Factors

15 Sept 2012

Abstract excerpt

Uropathogenic Escherichia coli (UPEC), which accounts for 85% of urinary tract infections (UTI), assembles biofilms in diverse environments, including the host. Besides forming biofilms on biotic surfaces and catheters, UPEC has evolved an intracellular pathogenic cascade that culminates in the formation of biofilm-like intracellular bacterial communities (IBCs) within bladder epithelial cells. Rapid bacterial...

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PMID: 22984258
DOI: 10.1128/jb.01012-12

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