Article

Selection for non-specific adhesion is a driver of FimH evolution increasing <i>Escherichia coli</i> biofilm capacity

2021-08-03

Abstract excerpt

<h4>ABSTRACT</h4> Bacterial interactions with surfaces rely on the coordinated expression and interplay of surface exposed adhesion factors. However, how bacteria dynamically modulate their vast repertoire of adhesins to achieve surface colonization is not yet well-understood. We used experimental evolution and positive selection for improved adhesion to investigate how an initially poorly adherent Escherichia c...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 79d46d64-2e08-5d23-979c-b7681cbadd84
DOI: 10.1101/2021.08.03.454899

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Selection for non-specific adhesion is a driver of FimH evolution increasing <i>Escherichia coli</i> biofilm capacityDOI 10.1101/2021.08.03.454899Read

Analysis of <i>in-patient</i> evolution of <i>Escherichia coli</i> reveals potential links to relapse of bone and joint infectionsSemantic proximity Read

Biofilm formation in a hydrodynamic environment by novel fimh variants and ramifications for virulence.Semantic proximity Read

Valency conversion in the type 1 fimbrial adhesin of Escherichia coli.Semantic proximity Read

Differential stability and trade-off effects of pathoadaptive mutations in the Escherichia coli FimH adhesin.Semantic proximity Read

Pathogenic adaptation of Escherichia coli by natural variation of the FimH adhesin.Semantic proximity Read

Molecular bases for the loss of type VI secretion system activity during enteroaggregative <i>E. coli</i> experimental evolutionSemantic proximity Read

Functional flexibility of the FimH adhesin: insights from a random mutant library.Semantic proximity Read

Success of <i>Escherichia coli</i> O25b:H4 ST131 clade C associated with a decrease in virulenceSemantic proximity Read

Molecular Characterization of the<i>Escherichia coli</i>FimH AdhesinSemantic proximity Read

Clonal analysis reveals high rate of structural mutations in fimbrial adhesins of extraintestinal pathogenic Escherichia coli.Semantic proximity Read

The affinity of the FimH fimbrial adhesin is receptor-driven and quasi-independent of Escherichia coli pathotypes.Semantic proximity Read

Context-dependent Requirements for FimH and Other Canonical Virulence Factors in Gut Colonization by Extraintestinal Pathogenic <i>Escherichia coli</i>Semantic proximity Read