Article
SNP rs7684318 of the alpha-synuclein gene is associated with Parkinson's disease in the Han Chinese population.
Brain research - 30 Jul 2010
Yu Lihua, Xu Pingrong, He Xianghua, Hu Fayun, Lin Zhenfang, Zhu Meirong, Liu Zhuolin, He Li, Xu Yanming
Abstract excerpt
Mutations in the alpha-synuclein (SNCA) gene have been shown to be responsible for a rare familial form of Parkinson's disease (PD). Furthermore, polymorphic variants in multiple regions of the gene have been associated with susceptibility to idiopathic PD in different populations. Previous studies in Japanese have found a strong association between idiopathic PD and the single-nucleotide polymorphism (SNP)...
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