Article
The alpha-synuclein gene and Parkinson disease in a Chinese population.
Archives of neurology - 1 Apr 2000
Chan D K, Mellick G, Cai H, Wang X L, Ng P W, Pang C P, Woo J, Kay R
Abstract excerpt
OBJECTIVE: To study the Ala53Thr and Ala30Pro mutations of the alpha-synuclein gene in a large number of Chinese patients with Parkinson disease (PD) as well as controls. METHODS: We recruited 183 Chinese patients with sporadic PD, 17 with younger-onset PD (onset age <50 years), and 7 with PD and a positive family history as well as 227 unaffected Chinese control subjects from the outpatient departments of 2...
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