Article
Genetic polymorphism in the persyn (gamma-synuclein) gene and the risk of Alzheimer's disease.
Neuroscience letters - 19 Feb 1999
Luedecking E K, Ganguli M, DeKosky S T, Kamboh M I
Abstract excerpt
Alzheimer's disease (AD) is a complex disease with the possible involvement of several genes. Genetic studies on sporadic late-onset AD have determined APOE*4 to be the major risk factor. Members of the synuclein gene family are potential candidates for the risk of AD. The persyn gene (gamma-synuclein) has recently been characterized and a common polymorphism (Glu110Val) has been identified. In this study we...
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