Article
Recirculating and marginal zone B cell populations can be established and maintained independently of primary and secondary follicles.
Immunology and cell biology - 1 Feb 2001
Körner H, Winkler T H, Sedgwick J D, Röllinghoff M, Basten A, Cook M C
Abstract excerpt
In normal spleen, most recirculating naïve IgM+IgDhi B cells are located within primary follicles and mantle zones of secondary follicles. By contrast, the marginal zone contains a heterogeneous population of IgMhiIgDlo/- B cells that are mostly non-recirculating. Although these are dynamic populations they are maintained at a constant size, the fundamental homeostatic mechanisms remain uncertain. One possibility...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.