Article
New insights into the cell biology of the marginal zone of the spleen.
International review of cytology - 1 Jan 2006
Kraal Georg, Mebius Reina
Abstract excerpt
In the marginal zone of the spleen the bloodstream passes through an open system of reticular cells and fibers in which various myeloid and lymphoid cells are located. Macrophages in this region are well equipped to recognize pathogens and filter the blood by virtue of unique combinations of pattern recognition receptors. They interact with a specific set of B cells that can be found only in the marginal zone and...
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