Article
An association study between 5-HTTLPR polymorphism, COMT polymorphism, and Tourette's syndrome.
Psychiatry research - 27 Dec 2000
Cavallini M C, Di Bella D, Catalano M, Bellodi L
Abstract excerpt
Several lines of evidence suggest that a genetic component underlies Tourette's syndrome (TS). We investigated both the role of the insertion/deletion polymorphism in the promoter region of the serotonin transporter gene (5-HTTLPR) and that of the Val-158-Met substitution in the catechol-O-methyl-transferase (COMT) gene in conferring susceptibility to TS. Fifty-two TS patients were recruited and compared with a...
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