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Article

A genetic variant of HTR2C may play a role in the manifestation of Tourette syndrome.

Psychiatric genetics - 1 Feb 2010

Dehning Sandra, Müller Norbert, Matz Judith, Bender Andreas, Kerle Irina, Benninghoff Jens, Musil Richard, Spellmann Ilja, Bondy Brigitta, Möller Hans-Juergen, Riedel Michael, Zill Peter

Abstract excerpt

Gilles de la Tourette syndrome (GTS) (MIM 137580) is a complex neuropsychiatric disorder probably originating from a disturbed interplay of several neurotransmitter systems in the prefrontal-limbic-basal ganglia loop. Polygenetic multifactorial inheritance has been postulated; nevertheless, no confirmed susceptible genes have been identified yet. As neuroimaging studies allude to dopaminergic and serotonergic...

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Source

Identifiers

PMID: 20010450
DOI: 10.1097/YPG.0b013e32833511ce

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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